Changchun Xinyang Trading Co., Ltd.

[Product Name] Opdivo
[Common Name] Nivolumab Injection
[English Name]
[Function and Indications] Nivolumab is a person's programmed death The receptor is suitable for blocking antibody therapy in patients with the following
⑴ Patients with unresectable or metastatic melanoma and ipilimumab [] and, if the mutation is positive, patients with disease progression after an inhibitor Treatment. This indication was approved under accelerated approval based on tumor response rate and durability of response. Continued approval for this indication may be contingent upon validation and description of clinical benefit in confirmatory trials.
⑵ Metastatic squamous non-small cell lung cancer that has progressed on or after platinum-based chemotherapy.
[Usage and Dosage] The recommended dose is to be administered as an intravenous infusion over 10 minutes per week until disease progression or unacceptable toxicity.
[Adverse Reaction] The most common adverse reaction (%) in patients with melanoma is rash. The most common adverse reactions (%) in patients with advanced squamous NSCLC were fatigue, dyspnea, musculoskeletal pain, decreased appetite, cough, nausea, nivolumab strength, and constipation.
[Notes] Administer glucocorticoids according to the severity of immune-mediated adverse reactions.
⑴ Withhold treatment for moderate immune-mediated pneumonia and permanently discontinue treatment for severe or life-threatening pneumonia.
⑵ Immune-mediated colitis is not given for moderate or severe and permanent termination for life-threatening colitis.
⑶ Immune-mediated hepatitis surveillance changes in liver function. Withhold for moderate and permanently discontinue for severe or life-threatening elevations in transaminases or total bilirubin.
⑷ The efficacy of nivolumab in immune-mediated nephritis and renal insufficiency is monitored by changes in renal function. Withhold for moderate and permanently discontinue for severe or life-threatening elevations in serum creatinine.
⑸ Immune-mediated hypothyroidism and hyperthyroidism monitor changes in thyroid function. Start thyroid hormone replacement when needed. (.)
⑹ Embryo-fetal toxicity may cause fetal harm. Advise on potential risks to the fetus and the use of effective contraception.
[Specification] Injection and/or solution in disposable vial
[] Bottle/box
[Price] * Yuan/box
* Yuan/box
【 Storage] Store at the bottom of the refrigerator. Protect nivolumab in its original packaging from light before use. Do not freeze or shake.
[Manufacturer] Bristol-Myers Squibb Company of the United States
[Supply Line]
[Customer Service]
[Contact Person] Liu Yanlan
[Business Philosophy]
⑴ Since its establishment, our company has insisted on treating drug quality as the life of the enterprise, adhering to the corporate philosophy of quality first, integrity first, and considerate service. Based on the operating principle of cost-benefiting quality and profit-benefiting customers, we are constantly striving for the cause of human health. Information
⑵ Our company takes serving public health as its own responsibility, relies on high-quality products, and takes differentiation and innovation as its market development principles. It has created a new path of corporate development and created integrity, fairness and justice. , pragmatic and enterprising corporate culture.
⑶ Our company's products are all original and come with inspection reports, certificates of conformity, anti-counterfeiting marks and detailed instructions. Quality absolutely guaranteed! New and old customers are welcome to call us to discuss and order
⑷ Our company does not provide free samples! Discounts available for large quantities! Door-to-door delivery is available locally, and orders from other provinces and cities can be delivered on time within two hours! Due to busy business, please don’t bother me if you are the one! Thank you for your cooperation