Changchun Xinyang Trading Co., Ltd.

[Common name] Treprostinil injection
[Commodity name] Remodulin
[English name Chenbr/> [Chinese Pinyin]
[Ingredients] This product The main ingredient is treprostinil.
【Chemical name】,), hexahydrohydroxy[hydroxyoctyl] benzo[]indenyl]oxy]acetic acid
【Molecular formula】
【Molecular weight】
【 Excipients] Sodium citrate dihydrate, hydrochloric acid, m-cresol, sodium hydroxide, sodium chloride, water for injection.
【Properties】This product is a colorless to slightly yellow clear liquid.
[Indications] This product is used to treat pulmonary arterial hypertension (, classification) to relieve related symptoms caused by exercise. Studies to establish the efficacy of this product have included patients with primary and hereditary pulmonary hypertension in functional class ~ (%), pulmonary hypertension associated with congenital systemic-to-pulmonary shunts (%), and patients with connective tissue disorders of pulmonary hypertension (%).
[Usage and Dosage] This product is packaged in a glass bottle and contains treprostinil. This product needs to be diluted with water for injection or .% injection before infusion. This product is administered subcutaneously or intravenously. The initial dose for patients receiving prostacyclin infusion therapy for the first time should only be administered as a continuous subcutaneous or intravenous infusion. Subcutaneous infusion is the preferred route of administration. However, if subcutaneous administration is not tolerated because of severe pain or reaction at the injection site, administration via a central venous catheter may also be used. The initial infusion rate is . If the initial dose cannot be tolerated due to systemic effects, the injection rate should be reduced to .
Dose Adjustment
The goal of long-term dose adjustment is to determine a dose of treprostinil that improves symptoms of pulmonary hypertension while reducing other pharmacological effects of the product (headache, nausea, vomiting, restlessness, anxiety and infusion site pain or reaction).
Adjust dosage according to clinical efficacy. The infusion rate increases by 1 per week during the first four weeks of treatment and 1 per week thereafter. Dose may be adjusted more frequently if tolerated. There is very little clinical experience with dosing. Abrupt cessation of the infusion should be avoided. Administration may be resumed at the same dose rate within a few hours of interruption, and dose re-titration may be necessary if the interruption is longer. Patients with hepatic insufficiency For patients with mild to moderate hepatic insufficiency, the initial dose of this product should be. The dosage should be calculated based on the ideal body weight. The dosage must be increased with caution. It has not been studied in patients with severe hepatic impairment.
Patients with Renal Impairment No studies have been conducted in patients with renal insufficiency.
[Dosage] Before injection administration, the medicine should be visually inspected for the presence of particulate matter and discoloration. If there are particles or discoloration in this product. then cannot be used.
[Specifications]
[Packaging] Stick/box
European Pharmacopoeia/American medicine typical colorless glass bottle, equipped with bromobutyl rubber stopper and aluminum easy-open sealing cap
Treprostinil (each product contains treprostinil), glass bottle packaging, stick/box.
[Price Description] Yuan/box
[Storage] ~ Save below.
[Validity period] Months
[Execution standards] Imported drug registration standards
[Approval number] Imported drug registration certificate number
[Company name] United Statesbr/> [Supply hotline ]
[Customer Service]
[Contact] Liu Yanlan
[Business Philosophy]
⑴ Since its establishment, our company has insisted on treating drug quality as the life of the enterprise, adhering to the principle of quality first and integrity first. , the corporate philosophy of considerate service, based on the operating principles of cost-benefiting quality and profit-benefiting customers, constantly working for the cause of human health
⑵ The company takes serving public health as its own responsibility and provides high-quality products Relying on the market development principles of differentiation and innovation, we have created a new path of corporate development and created a corporate culture of integrity, fairness, pragmatism and enterprising spirit.
⑶ Our company's products are all original and come with inspection reports, certificates of conformity, anti-counterfeiting marks and detailed instructions. Quality absolutely guaranteed! New and old customers are welcome to call us to discuss and order
⑷ Our company does not provide free samples! Discounts available for large quantities! Door-to-door delivery is available locally, and orders from other provinces and cities can be delivered on time within two hours! Due to busy business, please don’t bother me if you are the one! Thank you for your cooperation